Jana-Ch. Hegenbarth
Read Jana's blog posts:
1- From Molecular Biology to Bioinformatics 2- Science Untangled series: Logic 101 Project Title: Transcriptomic, placental blueprint from human and mouse preeclampsia or growth restriction and circulating miRNAs/lncRNAs
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Jana-Ch. Hegenbarth was born August 1993 in Recklinghausen, a town in the north-west of Germany. After receiving her Bachelor of science from the Faculty of Sciences of the University of Muenster (Germany) in 2015, she achieved her Master degree in Bioscience in August 2018 at the same university.
During her studies, Jana experienced the importance of bioinformatics in various fields and therefore, decided to write her Master thesis in the group of Prof. Dr. Monika Stoll at the university hospital of Muenster. In this period, she focused her attention on “A genome-wide association studies on variants in adult deep venous thrombosis” as the topic of her thesis. She also developed a strong interest in the influence of genetic and environmental factors on diseases and their medical importance.
She started to work as a PhD student and ESR within the iPlacenta consortium in the lab of Prof. Dr. Leon de Windt in October 2018 at the Molecular Cardiology group of the Department of Cardiology at the University of Maastricht. There, she studied the deep transcriptional differences between pre-eclamptic and healthy patients. During her almost 3 years as a PhD her project later shifted from the placenta to the heart. Her research focuses on understanding human induced pluripotent stem cells (hiPSCs) that are differentiated into cardiomyocytes (CM). This technique has emerged as a promising experimental tool for translational cardiac research and drug development. Her current goal is to identify all developmental changes in the transcriptome that hiPSC-CMs undergo from pluripotency to 3D-engineered heart muscle using recent single cell level methodologies. Her project further allowed Jana to work in collaborations with institutes in Göttingen (Germany) and Munich (Germany).
During her studies, Jana experienced the importance of bioinformatics in various fields and therefore, decided to write her Master thesis in the group of Prof. Dr. Monika Stoll at the university hospital of Muenster. In this period, she focused her attention on “A genome-wide association studies on variants in adult deep venous thrombosis” as the topic of her thesis. She also developed a strong interest in the influence of genetic and environmental factors on diseases and their medical importance.
She started to work as a PhD student and ESR within the iPlacenta consortium in the lab of Prof. Dr. Leon de Windt in October 2018 at the Molecular Cardiology group of the Department of Cardiology at the University of Maastricht. There, she studied the deep transcriptional differences between pre-eclamptic and healthy patients. During her almost 3 years as a PhD her project later shifted from the placenta to the heart. Her research focuses on understanding human induced pluripotent stem cells (hiPSCs) that are differentiated into cardiomyocytes (CM). This technique has emerged as a promising experimental tool for translational cardiac research and drug development. Her current goal is to identify all developmental changes in the transcriptome that hiPSC-CMs undergo from pluripotency to 3D-engineered heart muscle using recent single cell level methodologies. Her project further allowed Jana to work in collaborations with institutes in Göttingen (Germany) and Munich (Germany).
Nationality: German
Institution: Maastricht University
Supervisor: Prof Leon de Windt, Maastricht University
ResearchGate: Jana Hegenbarth
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