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We are recruiting 15-highly motivated candidates to become the next generation of scientists to drive translational research in maternal and fetal health. We will provide them with a 36-month multi-disciplinary PhD training programme coordinated among 11 academic, industrial and clinical institutes. The principal research aim of iPlacenta is to improve our ability to study, model and visualise the placenta to enhance investigation and prognosis of complicated pregnancies. Topics range from organ-on a chip technology, systems biology, various omics technology, miRNAs, preclinical in vivo modelling , clinical imaging and medical device technology. This multidisciplinary research will require potential candidates from subjects such as (but not limited to) molecular and cell biology, mathematics, physics, genetics, physiology and clinical imaging.
Benefits for the candidates Training: Students will receive scientific skills in cutting-edge techniques focusing on translational science in expert laboratories, in a highly stimulating and collaborative environment. Candidates will be involved in the particular project offered by the chosen hosting groups. In addition, all the students will receive specialised courses involving business OpenScience for OpenInnovation and entrepreneurship. Transferable skills will be embedded throughout the project. In addition, all the students will experience short term secondments in collaborative laboratories within the network. PhD: Students will register in the Doctorate program in their host institution or associated University. Salary: Students will have a highly competitive salary according to Marie Skłodowska-Curie Actions rules. Exact salary will be calculated per country and will include living and mobility allowances. Hosting conditions: Each recruited student will have a supervisor team to develop training and career plans. Find out more on iplacenta.eu or twitter #iPlacenta Applicants should complete the online application and upload documents send their by TBD. Any institutes with additional application requirements should also be completed. iPLACENTA committee will analyse all applications and eligible applications will be sent to the selected host laboratories. Selected candiates might be interviewed by Skype in April 2018. Final selection is expected to be finished in April 2018
Background and Rationale “The placenta is the least understood human organ but arguably one of the most important”-NIH Human Placenta Project. iPLACENTA. Two common pregnancy disorders preeclampsia (PE) and intrauterine growth restriction (IUGR) have great societal, patient & economic impact, yet our ability to treat these disorders is limited. Preeclampsia is a key challenge because its onset and clinical course are unpredictable, there are no preventative means and delivery is the only existing cure, which often necessitates medically induced preterm deliveries. Intrauterine growth restriction (IUGR) is the most common factor for stillborn babies, yet prediction rate is poor, two thirds of babies identified as possible IUGR are small but healthy for their gestational health. The remaining third are high risk for mortality, cerebral malformation. For those that survive both PE and IUGR, there are life-long serious cardiovascular and neurological consequences. The principal research aim of iPLACENTA is to improve our ability to study, model and visualise the placenta to enhance investigation and prognosis of complicated pregnancies such as PE and IUGR. iPLACENTA has developed a multi- disciplinary, network spanning different sectors. The research encompassed in iPLACENTA will boost the translational expertise in Maternal and Fetal Health (M&FH), training 15 ESRs to become world-leading pioneers in the international community by integrating organ-chip technology and mathematical modelling, with innovation in visualising and assessing placenta health in the clinic and in vivo models. The research will interconnect to unlock the complexity of placental disease, providing mechanistic clues for complex diseases, new ways to model placenta function in vitro, validate novel clinical diagnostic tools and characterise animal in vivo models. The PhD training programme will equip the ESRs with the necessary skills to meet the challenges of cutting-edge translational research alongside topics such as OpenScience, entrepreneurship, project management and business skills.